Saleema Amershi is a Partner Research Manager at Microsoft Research AI Frontiers, where she leads the teams behind AutoGen and Magentic-One. She joins the AI Inside podcast to discuss what happens when AI agents stop working in isolation and start collaborating, transacting, and negotiating with each other at scale. We cover the challenges of multi-agent orchestration, why current frontier models show a dangerous first-proposal bias that favors speed over quality, and how her team built the Magentic Marketplace to simulate agent-to-agent commerce. We also dig into agent manipulation, the tension between walled gardens and open ecosystems, and what duty of care means when an AI is acting on your behalf.
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